Botox, Xeomin & Dysport

Wrinkles are cute on puppies, for the rest of us there is Botox
Botox puppy with wrinkles

Neurotoxins to stop and smooth wrinkles

Do you buy Kleenex or do you buy tissues? Do you buy Band-Aids or do you buy adhesive bandages? Do you buy Jello or do you buy gelatin? These are all examples of a brand names becoming the product. In the case of Neurotoxins there is a selection. Botox, Dysport, Xeomin. So while we say Botox more often, there are other brand options.

Not all injection experiences are the same. We administer neurotoxins with a light touch. The goal is to lessen wrinkles without a frozen look or heavy feeling. At Refinery we prefer to administer neurotoxins sparingly. We want you to have the perfect look. If you think of the neurotoxins as a set of paint, then all injectors / artists are given the same sets of paint. But the results that each create are very different.

BOTOX® is injected into muscles and used to improve the look of moderate to severe frown lines between the eyebrows (glabellar lines) in people 18 to 65 years of age for a short period of time (temporary). It works by blocking nerve impulses to the injected muscles. This reduces muscle activity that causes moderate to severe lines to form between the brows. Individual results may vary. In the areas where the spread needs to be minimized, Botox may be the best option to concentrate on deeper wrinkling.  See photos of before & afters



Botox entered the market in 1989.

Discover the proven results that 11 million women and men have experienced. With real, noticeable results, no surgery and no recovery time, there are many reasons why BOTOX® Cosmetic has been chosen by millions of women and their doctors. You may feel that the moderate to severe glabellar lines between your brows make you look tired or unapproachable, or have other reasons for being curious about BOTOX® Cosmetic. Review safety information for Botox

Botox effectiveness over time
Xeomin alternative to Botox

Xeomin entered the market in 2011

First there was Botox, then there was Dysport, and now there is Xeomin (incobotulinumtoxinA). The FDA approved this new botulinum toxin type A product to treat severe frown lines or “11’s” between the eyebrows.

When you squint or frown, the muscles between your brows contract, causing the skin to furrow and fold. These lines that occur due to facial mimics are referred to as dynamic lines. Over time, as your skin ages and loses some of its elasticity, these repeated contractions can cause persistent frown lines.

Xeomin and Botox work the same way to paralyze muscles and smooth wrinkles. They share the identical active ingredient – botulinum toxin A. The difference is that Botox has an accompanying protein, but Xeomin is naked. In the skin, all of the protein detaches from Botox within 1 minute of injection so there is no reason why the effect of Xeomin should differ from Botox. Xeomin has proven effective in clinical trials. Xeomin is a purified neurotoxin. It is referred to as a ‘naked’ molecule (think the Whole Foods version of Botox) because there are no additive surface proteins, just the botulinum toxin. This solitary agent migrates further and faster to effectively work upon all facial areas upon injection. There is less risk of an allergic reaction or rejection for the client from the absence of protein additives.

xeomin before and after photos

Dysport-LogoDysport entered the market in 2009

One of the noted benefits of Dysport is that it spreads a little more than Botox and it is commonly used by patients who have stopped responding to Botox. It is also injected at a different strength and affects a slightly larger area than Botox and Xeomin. It has been reported that Dysport typically takes two to three days until the effects of the treatment are seen. Botox takes seven to ten days while Xeomin takes five to six days. Dysport may be the best option in areas where several injections are needed because of its easy spreading to cover a greater area on the face.


If you get Botox regularly be sure to sign up for Allergan’s Brilliant Distinction Program. You can learn more Xeomin many times has rebate offers. Be sure to ask for any promotions.

Don’t forget men! They come in just as often for their injections. Typically the number of units they need are more, but they want the same kind of results.

The first time you come to Refinery for Botox or Xeomin we are going to listen to what your goals are and give you our opinion. For the injections, we prefer to go light. You can always come back for more to get a stronger result, but we never want anyone leaving with a frozen appearance.


Botox and Xeomin are both $12 per unit. The number of units really does vary with the number of times you have been treated before, the amount of area you are covering, if it is a touch up or maintenance. But for general guidelines: bridge of nose, between eyes approx 15 units, crow’s feet approx 15 units total and forehead 15 units (men are different they need more). But this is a very general guideline.

The amount of neurotoxin used for wrinkle treatments is minor.  And in comparison to other treatments it is minuscule – a drop in the ocean.  Did you know a typical treatment for migraines uses up to 200 units?  Treatments for under arm sweating (hyperhidrosis) can use up to 150 units per arm.